From trend to health alert
Peptides are no longer a niche topic. In November 2025 the AP described unapproved peptide injections as a new fad among wellness influencers, fitness trainers and celebrities6. The promises range from fat loss and muscle recovery to anti-aging26. A 2026 review describes how digital promotion and gray-market access normalize products of uncertain identity, purity and sterility9. In 2026 regulators in the region responded.
Colombia: the full list
On June 24, 2026 INVIMA published Health Alert 184-2026. It named, one by one, products sold through an Instagram account and a website: DSIP, Selank, Semax, PT-141, ipamorelin, CJC-1295 without DAC, BPC-157, GHK-Cu, TB-500 and retatrutide1. INVIMA called them fraudulent, unregistered products that "have not been evaluated in terms of quality, safety or efficacy"1.
It is probably the official list closest to what people search for today when they type "peptides" into social media. Several of those names also appear on the World Anti-Doping Agency's 2026 Prohibited List: BPC-157 as a non-approved substance; ipamorelin, CJC-1295 and TB-500 among peptide hormones, growth factors and related substances13.
Guatemala: the Central American precedent
In August 2026 Guatemala's Ministry of Public Health warned that unregistered injectable peptides are being sold illegally, with products promoted online to burn fat, build muscle, boost performance or rejuvenate2. According to the report, the ministry stressed that every person has the right to know exactly what is being sold and injected into them2.
Mexico and PAHO: the GLP-1s
In March 2026 Cofepris warned about tirzepatide and other weight-loss products sold without registration on "e-commerce platforms, websites and mobile apps"3. Days earlier, on 27 February, PAHO had published a regional epidemiological alert on GLP-1 misuse, publicized on 3 March, warning about sales through unofficial channels, including the internet and social media4. Social media amplifies the trend: in a 2026 analysis of the 400 most popular TikTok videos on semaglutide and tirzepatide, 98% came from individual users or influencers, with lower reliability scores than content from health professionals10.
What about Panama?
As of this writing we found no MINSA alert aimed at peptides such as BPC-157 or TB-500. There is a precedent: in May 2024 the DNFD relayed an INVIMA alert on semaglutide-plus-B12 vials not registered in Panama and warned about sales online, on social media and WhatsApp5. In other words, the DNFD has already taken Colombian alerts and reissued them locally5.
Both sides of the debate
Promoters of these peptides point to animal studies and personal experience6. Regulators point to the lack of quality, safety and efficacy evaluation, and to the fact that buyers cannot verify what is in the vial12. When researchers bought semaglutide from illegal online pharmacies, the vials' measured purity was 7.7–14.4%, against 99% on the label, and all contained endotoxin8. For BPC-157, the FDA flags possible immunogenicity and peptide-related impurities; for the thymosin beta-4 fragment, it found no human exposure data14. A 2026 sports medicine review adds that rigorous human safety data are scarce and that social media amplifies the placebo effect11. And in a small 2026 study, 20 untrained adults relying only on internet information correctly completed 15 of 34 steps when trying to prepare a gray-market product12. Both sides agree that demand exists and is growing; the argument is over who answers for product quality126.
Sources
- INVIMA (Colombia). Alerta Sanitaria No. 184-2026: Péptidos fraudulentos. 24 de junio de 2026. app.invima.gov.co ↗
- Galicia S. El Ministerio de Salud de Guatemala advierte que los péptidos inyectables sin registro sanitario se venden de forma ilegal. Infobae. 6 de agosto de 2026. infobae.com ↗
- Expansión (México). Cuidado con estos productos para adelgazar: Cofepris alerta por riesgos graves al hígado y páncreas. 11 de marzo de 2026. expansion.mx ↗
- Organización Panamericana de la Salud. Ante reportes de uso indebido de medicamentos GLP-1 indicados para tratar la obesidad, la OPS pide reforzar la farmacovigilancia. 3 de marzo de 2026. paho.org ↗
- Ministerio de Salud de Panamá, DNFD. Comunicado 050/DNFD-2024: Alerta sobre el producto Semaglutida + Vitamina B12. 2 de mayo de 2024. minsa.gob.pa ↗
- Associated Press, vía El Nuevo Día. Una mirada más de cerca a las inyecciones de péptidos no aprobadas promovidas por influencers y famosos. 14 de noviembre de 2025. elnuevodia.com ↗
- Healio. FDA committee recommends looser restrictions for several peptides. 24 July 2026. healio.com ↗
- Ashraf AR, Mackey TK, Vida RG, Kulcsár G, et al. Multifactor Quality and Safety Analysis of Semaglutide Products Sold by Online Sellers Without a Prescription: Market Surveillance, Content Analysis, and Product Purchase Evaluation Study. J Med Internet Res. 2024;26:e65440. PubMed 39509151 ↗
- Hailu KT, Abriha FN, Duguma YM, Haddad RR, et al. Unregulated Peptide Use in the Age of Biohacking: Digital Promotion, Gray-Market Access, and Emerging Public Health Risks. Cureus. 2026;18(6):e110657. PubMed 42437212 ↗
- Günaltay MM, Kartal N. TikTokfluence: The rise of GLP-1 receptor agonists in the age of social media health trends. J Am Pharm Assoc (2003). 2026;66(3):103082. PubMed 41866128 ↗
- Mendias CL, Awan TM. Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance. Sports Med. 2026;56(8):1921-1935. PubMed 41966639 ↗
- Sedensky A, Nuzi K, Nolan L, Belcourt J, et al. Ability of Adults to Correctly Use Grey Market Peptide Semaglutide GLP-1 Receptor Agonists Acquired Without a Prescription. Public Health Rep. 2026:333549261464876. PubMed 42541373 ↗
- World Anti-Doping Agency. The 2026 Prohibited List (International Standard). Effective 1 January 2026. wada-ama.org ↗
- U.S. Food and Drug Administration. Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks. Content current as of 22 April 2026. fda.gov ↗
Informational article. It summarizes news, official statements and published studies; it is not medical or legal advice. Sources were checked on the publication date.